Can Crypto Accelerate Scientific Breakthroughs? w/ Tyler from Triplicate | Ep. 56
Tyler is putting Science back into the hands of the people. In episode #56 of Internet Explorers, Jess and Josh explore the forefront of decentralized science (DeSci) with Tyler from Triplicate, unpacking how blockchain is unlocking new funding models, democratizing research, and enabling cutting-edge projects like molecular therapeutics and patient-driven clinical trials. They analyze how these decentralized approaches are breaking free from the constraints of traditional institutions and incentivizing innovation in unexpected ways. The discussion shifts to distribution-first software, a paradigm focused on leveraging social networks and decentralized platforms to maximize reach and adoption before building standalone products. They also examine the concept of Moats in the age of AI, debating whether traditional business defensibility strategies hold up in a world of open-source models and rapidly evolving technologies. Later, they reflect on the growing presence of normies in degen crypto spaces, and the unhinged activities occurring on pump.fun (jess is scared). The episode concludes with ai16z drama, reflecting on how it's more difficult it is to build when a token is involved. 0:00 - Intro 1:08 - Start of Episode 4:26 - DeSci 37:07 - Distribution-First Software 42:38 - Moats In The Age Of AI 49:32 - The Normies Are Here 54:48 - ai16z Drama Internet Explorers is a weekly rundown show where extremely online individuals broadly explore (romanticize, even) new consumer internet experiences. Join us at live.seedclub.xyz on Fridays 10am PT / 1pm ET Seed Club Twitter: https://x.com/seedclubhq Internet Explorers Twitter: https://x.com/intrntexplorers Apple Music: https://podcasts.apple.com/us/podcast... Spotify: https://open.spotify.com/show/6iJk3xZ... Pods.media: https://pods.media/internet-explorers
This Will End Trader LARPs w/ wijuwiju.eth of Interface | Ep. 57
Finally, we know who the top trader is. In episode #57 of Internet Explorers, Jess and Josh delve into some of the most intriguing trends shaping Web3 and crypto. They kick things off with Interface, a platform that merges social networking with the blockchain, enabling users to build their social graph by copy-trading wallets and forming reputation-driven connections directly on-chain. The hosts reflect on the challenges and successes of developing consumer-focused blockchain products during a bear market and how Interface is carving out a niche with its discovery and trading features. The conversation then shifts to tokenomics, focusing on the evolution from complex whitepapers to meme-driven token launches. They explore the balance between capturing early belief and building utility over time, emphasizing the need for sustainability in token models. Other key topics include Capital Formation in the Reputation Era, where they examine how on-chain reputation is reshaping funding models, and Model Personality as a Moat, which highlights the growing role of AI in defining unique business defensibilities. The episode concludes with updates on Base’s resurgence and an exciting Lightning Round, featuring a creative vampire attack idea. 0:00 - Intro 0:26 - Start of Episode 4:09 - Interface 28:24 - Checking in on Tokenomics 39:53 - Capital Formation in the Reputation Era 47:48 - Model Personality as a Moat 52:40 - Base is Back 54:20 - A Stroll Through Consumer Crypto 55:52 - Lightning Round Internet Explorers is a weekly rundown show where extremely online individuals broadly explore (romanticize, even) new consumer internet experiences. Join us at live.seedclub.xyz on Fridays 10am PT / 1pm ET Seed Club Twitter: https://x.com/seedclubhq Internet Explorers Twitter: https://x.com/intrntexplorers Apple Music: https://podcasts.apple.com/us/podcast... Spotify: https://open.spotify.com/show/6iJk3xZ... Pods.media: https://pods.media/internet-explorers
